Alpha-1 Antitrypsin Deficiency—commonly called AATD— or Alpha-1is a genetic disorder that increases a person’s changes of developing emphysema, COPD and other diseases of the lungs. People with AATD are missing the protein antitrypsin that protects the lungs from damage caused by infection and inhaled irritants. Abnormally formed antitrypsin can also accumulate in the liver. So the problem is while Alpha-1 can lead to both severe lung and liver disease estimates are more than 90 percent of the people who have this deficiency don’t know it. But there are treatments available as we’ll see in this program. There are also support groups that can help people with Alpha-1learn about the condition—and how to effectively manage it. (2806)
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